Clinical Leader
Cristina Ripoll
JOB TITLE
Associate Professor, Internal Medicine IV (Hepatology Expert NASH/NAFLD)
ROLE
Clinical Leader of Use Case #3: Cardiovascular events post TIPS placement (Portal Hypertension) and liver transplant
INSTITUTION
Universitäts klinikum Jena (JUH)
Scientific Leader
Irène Vignon-Clementel
JOB TITLE
Prof. Dr. Scientific Leader
ROLE
ARTEMIs Scientific Coordinator and Scientific Leader of Use Case #3: Cardiovascular events post TIPS placement
(Portal Hypertension) and liver transplant
INSTITUTION
Institut national de recherche
en sciences et technologies du
numérique (INRIA)
Case overview
Use case 3 evaluates the liver heart interaction in patients with end-stage liver disease (cirrhosis) with clinical complications. Patients who have decompensated cirrhosis frequentyl require treatments like TIPS (transjugular intrahepatic portosystemic shunt) for portal hypertension. With TIPS insertion a shortcut for the blood that comes from the gut is created, so that it can partially bypass the liver and therefore a reduction in portal pressure takes place. Another treatment option is liver transplantation (LT), which is a surgical procedure in which the diseased liver is removed and a new liver is inserted. Both procedures are life saving but have complications, including heart complications.
